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The antimicrobial effect of a novel peptide LL-1 on Escherichia coli by increasing membrane permeability.

Mingliang ZhangKaiqi LianMengting WangXueyi JingYuanchen ZhangJin-Ling Cao
Published in: BMC microbiology (2022)
This study indicated that LL-1 had a good bactericidal effect on E. coli by mainly increasing the permeability of the cell membrane, leading to leakage of the intracellular content. This will lay the foundation for an in-depth study on the antibacterial mechanism of LL-1 against E. coli and its clinical application.
Keyphrases
  • escherichia coli
  • staphylococcus aureus
  • endothelial cells
  • cystic fibrosis
  • biofilm formation
  • reactive oxygen species
  • essential oil