Deletion of Schizophrenia Susceptibility Gene Ulk4 Leads to Abnormal Cognitive Behaviors via Akt-GSK-3 Signaling Pathway in Mice.

Ling HuBing-Yao ZhouCui-Ping YangDa-Yun LuYun-Chao TaoLin ChenLei ZhangJun-Hui SuYing HuangNing-Ning SongJia-Yin ChenLi ZhaoYi ChenChun-Hui HeYu-Bing WangBing LangYu-Qiang Ding

Published in: Schizophrenia bulletin (2022)

Our data identified potential downstream signaling pathway of Ulk4, which plays important roles in the cognitive functions and when defective, may promote SCZ-like pathogenesis and behavioral phenotypes in mice.

Keyphrases

signaling pathway
pi k akt
epithelial mesenchymal transition
high fat diet induced
induced apoptosis
bipolar disorder
cell proliferation
copy number
type diabetes
machine learning
transcription factor
skeletal muscle
genome wide identification