Comparison of PIK3CA Mutation Prevalence in Breast Cancer Across Predicted Ancestry Populations.

Jessica W Chen Karthikeyan MurugesanJustin Y NewbergEthan S SokolHeidi M SavageThomas J StoutSophia L MaundKatherine E Hutchinson

Published in: JCO precision oncology (2022)

mut prevalence can differ among predicted genetic ancestries across BC subtypes on the basis of the largest comprehensive genomic profiling data set of patients with cancer treated in the United States. This study highlights the need for equitable representation in research studies, which is imperative to ensuring better health outcomes for all.

Keyphrases

risk factors
copy number
electronic health record
single cell
genome wide
big data
dna methylation
case control
genetic diversity
protein kinase