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Building a Pharmacogenomics Knowledge Model Toward Precision Medicine: Case Study in Melanoma.

Hongyu KangJiao LiMeng WuLiu ShenLi Hou
Published in: JMIR medical informatics (2020)
We highlighted the pharmacogenomics knowledge model as a scalable framework for clinicians and clinical pharmacists to adjust drug dosage according to patient-specific genetic variation, and for pharmaceutical researchers to develop new drugs. In the future, a series of other antitumor drugs and automatic relation extractions will be taken into consideration to further enhance our framework with more PGx linked data.
Keyphrases
  • healthcare
  • adverse drug
  • deep learning
  • electronic health record
  • palliative care
  • emergency department
  • big data
  • primary care