Therapeutic Effects of IL-1RA, M2 Cells, and Their Synergistic Impact on a Mouse Model of Rheumatoid Arthritis.

Mohammad Sadegh HashemzadehHadi Esmaeili Gouvarchin GhalehMozafar MohammadiYaser YousefpoorEhsan RezaeiGholamhossein Alishiri

Published in: Advanced pharmaceutical bulletin (2024)

The simultaneous use of IL-1RA and M2 cells could be a promising approach for the treatment of RA. This combinatory therapy has the potential to improve the disease and decrease the severity of inflammation in patients with RA.

Keyphrases

rheumatoid arthritis
disease activity
induced apoptosis
cell cycle arrest
mouse model
ankylosing spondylitis
oxidative stress
interstitial lung disease
systemic lupus erythematosus
cell death
endoplasmic reticulum stress
signaling pathway
stem cells
risk assessment
pi k akt