Annona muricata Linn and Khaya grandifoliola C.DC. Reduce Oxidative Stress In Vitro and Ameliorate Plasmodium berghei-Induced Parasitemia and Cytokines in BALB/c Mice.

Onohuean HopeAbdullateef I AlagbonsiIbe Michael Usman Keneth Iceland KasoziAthanasios AlexiouReem H BadrGaber El-Saber BatihaJoseph Obiezu Chukwujekwu Ezeonwumelu

Published in: Journal of evidence-based integrative medicine (2021)

The ethanol extracts of A. muricata and K. grandifoliola reduce parasitemia in P. berghei-treated mice BALB/c by scavenging free radicals and reducing cytokines, though the extracts were not as effective as chloroquine.

Keyphrases

oxidative stress
diabetic rats
high fat diet induced
high glucose
dna damage
plasmodium falciparum
dendritic cells
type diabetes
insulin resistance
metabolic syndrome
wild type
induced apoptosis
endothelial cells
endoplasmic reticulum stress