The Epidome - a species-specific approach to assess the population structure and heterogeneity of Staphylococcus epidermidis colonization and infection.
Amalie Katrine RendboeThor Bech JohannesenAnna Cäcilia InghamEmeli MånssonSøren IversenSharmin BaigSofie EdslevJørgen Skov JensenBo SöderquistPaal Skytt AndersenMarc SteggerPublished in: BMC microbiology (2020)
The Epidome method is designed for use on primary samples to obtain important information on S. epidermidis abundance and diversity beyond species-level to answer questions regarding the emergence and dissemination of nosocomial lineages, investigating clonality of S. epidermidis communities, population dynamics, and niche selection. Our targeted-sequencing method allows rapid differentiation and identification of clinically important nosocomial lineages in low-biomass samples such as skin samples.
Keyphrases
- biofilm formation
- staphylococcus aureus
- pseudomonas aeruginosa
- single cell
- acinetobacter baumannii
- escherichia coli
- methicillin resistant staphylococcus aureus
- klebsiella pneumoniae
- wastewater treatment
- cancer therapy
- health information
- multidrug resistant
- microbial community
- antibiotic resistance genes
- loop mediated isothermal amplification