Inhibition of Protein-Protein Interactions: New Options for Developing Drugs against Neglected Tropical Diseases.
Thorsten BergPublished in: Angewandte Chemie (International ed. in English) (2017)
Wake up! Sleeping sickness and Chagas disease are neglected tropical diseases caused by trypanosome infections. Small molecules that disrupt a crucial protein-protein interaction in the parasites offer a new approach to drug development for these diseases.