Paramagnetic rim lesions are associated with pathogenic CSF profiles and worse clinical status in multiple sclerosis: A retrospective cross-sectional study.
Christopher C HemondJonggyu BaekCarolina IoneteDaniel S ReichPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)
PRLs, an emerging noninvasive biomarker of chronic neuroinflammation, are confirmed to be associated with greater disease severity and newly shown to be preliminarily associated with blood-brain barrier disruption.