Comparative Analysis of Ischemia-Reperfusion Injury in Heart Transplantation: A Single-Center Study Evaluating Conventional Ice-Cold Storage versus the Paragonix SherpaPak Cardiac Transport System.
Dor LotanCathrine M MoellerAfsana RahmanGal RubinsteinDaniel OrenYonatan MehlmanAndrea Fernandez ValledorErsilia M DeFilippisJayant K RaikhelkarKevin D ClerkinJustin FriedDavid T MajureYoshifumi NakaYuji KakuKoji TakedaKyung Taek OhAdil YunisPaolo C ColomboMelana YuzefpolskayaFarhana LatifGabriel SayerNir UrielMiroslav SekulicPublished in: Clinical transplantation (2024)
The CTS preservation system had similar rates of IRI and clinical outcomes compared to ICS despite longer overall ischemic times. There is significantly more recovery of IRI in the early post operative period with CTS. This study supports CTS as a viable option for preservation from remote locations, expanding the donor pool.