Improvement of cytotoxicity of mitoxantrone and daunorubicin by candidone, tephrosin, and bavachinin.

Sina DarziSeyed Abbas MirzaeiFatemeh ElahianAmir PeymaniBabak RahmaniShaghayegh Pishkhan DibazarSadegh ShirianLeila Shakeri ChaleshtoriEhsan Aali

Published in: Molecular biology reports (2021)

This effect is not time-dependent, and flavonoids have their own patterns that are cell-dependent. In general, tephrosin, candidone, and bavachinin had the potential of sensitizing MDR cells to mitoxantrone and daunorubicin.

Keyphrases

induced apoptosis
cell cycle arrest
single cell
multidrug resistant
cell therapy
endoplasmic reticulum stress
oxidative stress
cell death
bone marrow
pi k akt