Aberrant frontostriatal connectivity in Alzheimer's disease with positive palmomental reflex.

Hannes GramespacherN RichterS Edwin ThanarajahH I L JacobsK N H DillenN NellessenB von ReuternJ DronseJ KukoljaG R FinkOezguer A Onur

Published in: European journal of neurology (2020)

Data suggest that dysfunction of the CMC reflected by decreased FC underlies a positive PMR in patients with AD. The lack of significant grey matter or SC differences might reflect that changes in FC appear before changes in SC in the structures of the CMC and brain atrophy.

Keyphrases

white matter
resting state
functional connectivity
multiple sclerosis
oxidative stress
electronic health record
cognitive decline
high resolution
machine learning
mass spectrometry
blood brain barrier