Staphylococcal enterotoxin IgE sensitization in late-onset severe eosinophilic asthma in the elderly.
Heung-Woo ParkI SintobinK-H SohnM-G KangH-K ParkE-J JoS-E LeeM-S YangS-H KimH-K ParkY E KwonT-B KimS-H KimH-W ParkY-S ChangB-J LeeY-K JeeB W ChoiC BachertS-H ChoPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2016)
This is the first report on the significant associations of SE-IgE sensitization with late-onset asthma in the elderly, particularly severe eosinophilic asthma with CRS comorbidity. Our findings indicate a potential implication of SE in the high morbidity burden of elderly asthma and suggest clues to the pathogenesis of severe late-onset eosinophilic asthma in the elderly.