FOXC1 and FOXC2 maintain mitral valve endothelial cell junctions, extracellular matrix, and lymphatic vessels to prevent myxomatous degeneration.

Can TanShreya KurupYaryna DyakivTsutomu Kume

Published in: bioRxiv : the preprint server for biology (2023)

are required for maintaining the integrity of the MV, including VEC junctions, ECM organization, and lymphatic vessels to prevent myxomatous mitral valve degeneration.

Keyphrases

mitral valve
extracellular matrix
single molecule
lymph node
left atrial
endothelial cells
left ventricular
high glucose
atrial fibrillation