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Serum microRNA-122 and Wisteria floribunda agglutinin-positive Mac-2 binding protein are useful tools for liquid biopsy of the patients with hepatitis B virus and advanced liver fibrosis.

Masato NakamuraTatsuo KandaXia JiangYuki HagaKoji TakahashiShuang WuShin YasuiShingo NakamotoOsamu Yokosuka
Published in: PloS one (2017)
A lower serum miR-122 level is a useful predictor of advanced liver fibrosis in HBV-infected patients. Serum WFA(+)-M2BP could predict liver fibrosis in both HBV and HCV infection. The combination of these markers may result in the more accurate evaluation of liver fibrosis in HBV infection.
Keyphrases
  • liver fibrosis
  • hepatitis b virus
  • liver failure
  • binding protein
  • cell proliferation
  • hepatitis c virus
  • high resolution
  • mass spectrometry
  • ionic liquid