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Integrated epigenomic analysis stratifies chromatin remodellers into distinct functional groups.

Katherine A GilesCathryn M GouldQian DuKsenia SkvortsovaJenny Z SongMadhavi P MaddugodaJoanna Achinger-KaweckaClare StirzakerSusan J ClarkPhillippa C Taberlay
Published in: Epigenetics & chromatin (2019)
Our findings suggest that chromatin remodelling events are synchronous and that chromatin remodellers themselves should be considered simultaneously and not as individual entities in isolation or necessarily by structural similarity, as they are traditionally classified. Their coordinated function should be considered by preference for chromatin features in order to gain a more accurate and comprehensive picture of chromatin regulation.
Keyphrases
  • dna damage
  • gene expression
  • transcription factor
  • genome wide
  • dna methylation
  • high resolution