Transcranial direct current stimulation (tDCS) and trigeminal pain: A preclinical study.

Etiane Micheli Meyer CallaiVanessa Leal ScarabelotLiciane Fernandes MedeirosCarla de OliveiraAndressa de SouzaIsabel Cristina MacedoStefania Giotti CioatoFabrício FinamorWolnei CaumoAlexandre da Silva QuevedoIraci Lucenada Silva Torres

Published in: Oral diseases (2019)

Chronic constriction of the infraorbital nerve model was effective in establishing trigeminal neuropathic pain on 14 days after surgery, and tDCS reduced allodynia and LDH serum levels and promoted alterations in NGF, TNF-α, and IL-10 brainstem levels. Thus, we suggest that tDCS may be a potential therapy in the trigeminal pain treatment.

Keyphrases

neuropathic pain
transcranial direct current stimulation
spinal cord
spinal cord injury
working memory
rheumatoid arthritis
chronic pain
growth factor
cell therapy
risk assessment
bone marrow
peripheral nerve
combination therapy
pain management