Visceral Leishmaniasis Revealing Undiagnosed Inborn Errors of Immunity.

Daniel Gleison Carvalho Dewton de Moraes Vasconcelos Andreia Cristiane Rangel Santos José Angelo Lauletta Lindoso

Published in: Revista da Sociedade Brasileira de Medicina Tropical (2023)

Visceral Leishmaniasis (VL) is a potentially fatal disease and may be associated with primary or acquired immunodeficiencies. There are few reports, in the literature, of inborn errors of immunity. Here, we report two cases of VL as a marker of inborn errors of immunity, namely, GATA2 and RAB27A deficiency. Our data suggest that VL patients should be screened for primary immunodeficiency, particularly in cases of VL relapse.

Keyphrases

adverse drug
end stage renal disease
patient safety
newly diagnosed
systematic review
chronic kidney disease
electronic health record
prognostic factors
big data
free survival
data analysis