Trisomy 8 mosaicism in the placenta: A Danish cohort study of 37 cases and a literature review.

Simon Horsholt Thomsen Ida Charlotte Bay LundChristina FagerbergIben BacheNaja BecherIda Vogel

Published in: Prenatal diagnosis (2020)

T8M detected in CVS poses a significant risk of fetal involvement, and examination of amniotic fluid (AF) and/or fetal tissue should be offered. However, a normal result of AF still has a considerable residual risk of fetal involvement. Genetic counselling at an early gestational age is essential, and follow-up ultrasonography should be performed to predict fetal involvement if possible.

Keyphrases

gestational age
atrial fibrillation
birth weight
preterm birth
genome wide
dna methylation
case report
gene expression
physical activity
computed tomography
contrast enhanced
mesenchymal stem cells
human immunodeficiency virus