miR-186-5p targets TGFβR2 to inhibit RAW264.7 cell migration and proliferation during mouse skin wound healing.

Yinglei WangYuansheng LiDan NiZiqi WeiZhe FuChao LiHuiling SunYutong WuYilin LiYingxuan ZhangNaixin LiuYixiang LiuZhuo WangJiayi LiDandan SunLi HeYing YangYing WangMeifeng Yang

Published in: Environmental toxicology (2023)

miR-186-5p regulated macrophage migration and proliferation to delay wound healing through the TGFβR2/Smad2/p38 molecular axes, thus providing a promising new pro-repair drug target.

Keyphrases

wound healing
cell migration
transforming growth factor
signaling pathway
epithelial mesenchymal transition
adipose tissue
transcription factor
anti inflammatory
single molecule
drug induced
soft tissue