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HLA-DQA1*05 Was Not Associated With Primary Nonresponse or Loss of Response to First Anti-TNF in Real-World Inflammatory Bowel Disease Patients.

Andrea Pascual-OliverDiego Casas DezaCamila CuaránSantiago García-LópezPilar Corsino-RocheEva Sierra-MorosPilar Olier-MartínezRicardo González-TarancónRaquel Vicente-Lidón
Published in: Inflammatory bowel diseases (2023)
In our real-life cohort of IBD patients treated for the first time with anti-TNF, being an HLA-DQA1*05 carrier did not act as a predictor of response failure, either primary or secondary. The safety of anti-TNF treatment has also not been influenced by the variant.
Keyphrases
  • rheumatoid arthritis
  • end stage renal disease
  • ejection fraction
  • chronic kidney disease
  • peritoneal dialysis
  • ulcerative colitis
  • smoking cessation