Effects of L-/N-Type Calcium Channel Blockers on Angiotensin II-Renin Feedback in Hypertensive Patients.
Yutaka KawabataTakeshi SoekiHiroyuki ItoTomomi MatsuuraKenya KusunoseTakayuki IseKoji YamaguchiTakeshi TobiumeShusuke YagiDaiju FukudaHirotsugu YamadaTetsuzo WakatsukiMitsuhiro KitaniKazuhiro KawanoYoshio TaketaniMasataka SataPublished in: International journal of hypertension (2020)
The L-/N-type CCB cilnidipine, but not amlodipine, decreased urinary albumin excretion in hypertensive patients. Cilnidipine also increased the ratio of Ang-(1-7) to angiotensin II in plasma, which might be one factor underlying its beneficial effects.