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Repurposing auranofin to combat uropathogenic Escherichia coli biofilms.

H-I JangYong-Bin Eom
Published in: Journal of applied microbiology (2019)
Our study strongly suggest that auranofin is a promising alternative anti-biofilm and antimicrobial agent to prevent UPEC biofilm formation in UTIs. Auranofin already approved for human use have the advantage of being able to be put into clinical use relatively quickly.
Keyphrases
  • biofilm formation
  • escherichia coli
  • candida albicans
  • staphylococcus aureus
  • pseudomonas aeruginosa
  • endothelial cells
  • cystic fibrosis
  • klebsiella pneumoniae
  • induced pluripotent stem cells