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Fetal growth restriction followed by very preterm birth is associated with smaller kidneys but preserved kidney function in adolescence.

Jonas LiefkeCaroline HeijlKatarina Steding-EhrenborgEva MorsingHåkan ArhedenDavid LeyErik Hedström
Published in: Pediatric nephrology (Berlin, Germany) (2022)
FGR with abnormal fetal blood flow followed by very preterm birth is associated with smaller total kidney and medullary kidney volumes, but not with markers of kidney dysfunction or RAAS activation in adolescence. Decreased total kidney and medullary volumes may still precede a long-term decrease in kidney function, and potentially be used as a prognostic marker. A higher resolution version of the Graphical abstract is available as Supplementary information.
Keyphrases
  • preterm birth
  • blood flow
  • low birth weight
  • gestational age
  • depressive symptoms
  • oxidative stress