Quantitative Diffusion-Weighted Imaging Analyses to Predict Response to Neoadjuvant Immunotherapy in Patients with Locally Advanced Head and Neck Carcinoma.
Hedda J van der HulstJoris L VosRenaud TissierLaura A SmitRoland M MartensRegina G H Beets-TanMichiel W M van den BrekelCharlotte L ZuurJonas A CastelijnsPublished in: Cancers (2022)
Pre-treatment DWI tumor diameter and sphericity may be quantitative biomarkers for the prediction of an early pathological response to ICB. Furthermore, our data indicate that ADC skewness could be a marker for individual response evaluation.
Keyphrases
- diffusion weighted imaging
- locally advanced
- rectal cancer
- magnetic resonance imaging
- contrast enhanced
- neoadjuvant chemotherapy
- squamous cell carcinoma
- high resolution
- radiation therapy
- phase ii study
- lymph node
- diffusion weighted
- electronic health record
- magnetic resonance
- computed tomography
- mass spectrometry
- optical coherence tomography