Specific TCR gene rearrangements in mycosis fungoides: does advanced clinical stage show a preference?

Etan MarksYanhua WangYang ShiJoseph SusaMark JacobsonD Yitzchak Goldstein

Published in: Journal of clinical pathology (2018)

The presence of a single TCR gene rearrangement in the Vɣ1-8 region could possibly be related to a more advanced stage of MF. However, more comprehensive studies, such as next generation sequencing, with a larger cohort is necessary for a more definitive conclusion.

Keyphrases

copy number
regulatory t cells
genome wide
genome wide identification
gene expression
immune response
case control
genome wide analysis
circulating tumor cells