Rates, Predictors, and Outcomes of Portal Lymphadenectomy for Resectable Gallbladder Cancer.
Phillip M Kemp BohanAnne E O'SheaOriana V EllisRobert C ChickAlex M ClemDerek T KirbyJulia O BaderTimothy E NewhookG Travis CliftonChing-Wei D TzengDaniel W NelsonTimothy J VreelandPublished in: Annals of surgical oncology (2021)
LND is associated with a 48% reduction in risk of death in patients with resectable non-metastatic GBC, with greatest impact in pT2-3 patients. Patients without LND have similar OS to patients with node-positive disease, highlighting the importance of LND. Underutilization of LND likely results in undertreatment of patients with undiagnosed nodal disease, which may contribute to unfavorable oncologic outcomes.