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The role of precision medicine in bronchiectasis: Emerging data and clinical implications.

Grace OsculloDavid la Rosa-CarrilloMarta Garcia ClementeRosa GironRafael GolpeLuis MáizMiguel Angel Martínez-García
Published in: Expert review of respiratory medicine (2023)
True precision or personalized medicine is based on concepts that have not yet been fully achieved in bronchiectasis, although some authors are already beginning to adapt them to this disease in terms of pulmonary and extrapulmonary aetiologies, clinical fingerprinting (specific to each individual), cellular biomarkers such as neutrophils and eosinophils (in peripheral blood) and molecular biomarkers such as neutrophil elastase. In therapeutic terms, the future is promising, and some molecules with significant antibiotic and anti-inflammatory properties are being developed.
Keyphrases
  • peripheral blood
  • cystic fibrosis
  • anti inflammatory
  • pulmonary hypertension
  • electronic health record
  • big data
  • current status
  • artificial intelligence
  • machine learning
  • deep learning