Interference in melanoma CD248 function reduces vascular mimicry and metastasis.

Cheng-Hsiang KuoYa-Fang WuBi-Ing ChangChao-Kai HsuChao-Han LaiHua-Lin Wu

Published in: Journal of biomedical science (2022)

CD248 expression in melanoma cells promotes malignant transformation by increasing the activity of cell adhesion, migration, and vascular mimicry, whereas rCD248 protein functions as a molecular decoy interfering with tumor-promoting effects of CD248 in melanoma cells.

Keyphrases

cell adhesion
nk cells
binding protein