Thrombophilic Risk of Factor V Leiden, Prothrombin G20210A, MTHFR, and Calreticulin Mutations in Essential Thrombocythemia Egyptian Patients.
Mohammed Sabry El-GhonemySolafa El SharawyMaryan Waheeb FahmiShaimaa El-AshwahMay DenewerMohamed ElbaiomyPublished in: Advances in hematology (2020)
There is a significant increase risk of thrombosis in ET patients with CALR mutation, thrombophilic mutations, as well as factor V Leiden and prothrombin gene mutation with a risk of developing leukemic transformation.