Mining ancient microbiomes using selective enrichment of damaged DNA molecules.

Clemens L WeißMarie-Theres GansaugeAyinuer Aximu-PetriMatthias MeyerHernán A Burbano

Published in: BMC genomics (2020)

Our experiments show, that in addition to its use in enriching authentic endogenous DNA of organisms of interest, the selective enrichment of damaged DNA molecules can be a valuable tool in the discovery of ancient microbial taxa.

Keyphrases

circulating tumor
cell free
single molecule
small molecule
nucleic acid
high throughput
gram negative
multidrug resistant
single cell