Sigma-2 receptor/TMEM97 agonist PB221 as an alternative drug for brain tumor.
Chia-Chi LiuChing-Fang YuShu-Chi WangHsueh-Yin LiChiu-Min LinHsia-Han WangCarmen AbateChi-Shiun ChiangPublished in: BMC cancer (2019)
This study demonstrates that the sigma-2 receptor agonist PB221 has the potential to be an alternative chemotherapeutic drug for brain tumors with comparable side effects as the current standard-of-care drug, temozolomide.