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Comparative two time-point proteome analysis of the plasma from preterm infants with and without bronchopulmonary dysplasia.

Magdalena ZasadaMaciej SuskiRenata BokiniecMonika Szwarc-DumaMaria Katarzyna Borszewska-KornackaJózef MadejBeata Bujak-GiżyckaAnna Madetko-TalowskaCecilie RevhaugLars O BaumbuschOla D SaugstadJacek Józef PietrzykPrzemko Kwinta
Published in: Italian journal of pediatrics (2019)
BPD development is associated with the plasma proteome changes in preterm infants, adding further evidence for the possible involvement of disturbances in vitamin E availability and impaired immunological processes in the progression of prematurity pulmonary complications. Moreover, it also points to the differences in proteins related to infection resistance and maintaining an adequate level of hematocrit in infants diagnosed with BPD.
Keyphrases
  • preterm infants
  • low birth weight
  • pulmonary hypertension
  • drug induced