Effect of Primary Tumor Location on Postmetastasectomy Survival in Patients with Colorectal Cancer Liver Metastasis.
Tien-Hua ChenWei-Shone ChenJeng-Kai JiangShung-Haur YangHuann-Sheng WangShih-Ching ChangYuan-Tzu LanChun-Chi LinHung-Hsin LinSheng-Chieh HuangHou-Hsuan ChengGar-Yang ChauCheng-Yuan HsiaHao-Jan LeiShu-Cheng ChouYee ChaoHao-Wei TengPublished in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2020)
The CRLM post-hepatic-metastasectomy OS was superior in left-sided colon cancer than in right-sided colon cancer and was similar in rectal and right-sided colon cancer. The OS difference in different primary tumor locations is dependent on KRAS mutation status, with a decreased left- versus right-sided death risk noted only in KRAS wild-type colon cancer and an increased rectal versus right-sided death risk noted only in KRAS mutant colon cancer.
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