Relationship between donor fraction cell-free DNA and clinical rejection in heart transplantation.

Shriprasad R Deshpande Steven D ZangwillSteven J KindelJacob N SchroderDavid P BichellMark A WiggerMarc E RichmondKenneth R KnechtElfriede PahlNunzio A GaglianelloWilliam T MahleKarl D StammPippa M SimpsonMahua DasguptaLiyun ZhangPaula E NorthAoy Tomita-MitchellMichael E Mitchell

Published in: Pediatric transplantation (2022)

DF cfDNA has excellent agreement with clinical rejection and, importantly, serial measurement of DF cfDNA predict clinically significant outcomes post treatment for rejection in these patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
patient reported outcomes
adipose tissue
weight loss
replacement therapy