Fusion Kinases Identified by Genomic Analyses of Sporadic Microsatellite Instability-High Colorectal Cancers.

Kazuhito Sato Masahito KawazuYoko YamamotoToshihide UenoShinya KojimaGenta NagaeHiroyuki ManoManabu SodaTakafumi OgaShinji KohsakaEirin SaiYoshihiro YamashitaHisae IinumaMasashi FukayamaHiroyuki AburataniToshiaki WatanabeHiroyuki Mano

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)

We discovered that fusion kinases are frequently observed among sporadic MM MSI-H colorectal cancers. The new method to identify MM tumors enables us to straightforwardly group MSI-H patients into candidates of LS or fusion kinase carriers.

Keyphrases

end stage renal disease
late onset
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
copy number
young adults
protein kinase