Effects of Aqueous Dispersions of C60, C70 and Gd@C82 Fullerenes on Genes Involved in Oxidative Stress and Anti-Inflammatory Pathways.
Elena V ProskurninaIvan V MikheevEkaterina A SavinovaElizaveta S ErshovaNatalia N VeikoLarisa V KamenevaOlga A DolgikhIvan V RodionovMikhail A ProskurninSvetlana V KostyukPublished in: International journal of molecular sciences (2021)
The aqueous dispersions of C60, C70, and Gd@C82 fullerenes are active participants in reactive oxygen species (ROS) homeostasis. Low and high concentrations of aqueous fullerene dispersions (AFD) have similar effects. C70 was the most inert substance, C60 was the most active substance. All AFDs have both "prooxidant" and "antioxidant" effects but with a different balance. Gd@C82 was a substance with more pronounced antioxidant and anti-inflammatory properties, while C70 had more pronounced "prooxidant" properties.