Differential seminal plasma proteome signatures of boars with high and low resistance to hypothermic semen preservation at 5°C.
Tila de Alcantara MenezesIvan Cunha Bustamante-FilhoAline Fernanda Lopes PaschoalPedro Ferrari DalbertoCristiano Valim BizarroMari Lourdes BernardiRafael da Rosa UlguimFernando Pandolfo BortolozzoAna Paula Gonçalves MellagiPublished in: Andrology (2020)
Differences in the seminal plasma suggest that proteins involved in the proteolytic activation of metalloproteinases and proteins related to immune response modulation could disrupt key cellular pathways during spermatogenesis and epididymal maturation, resulting in altered resistance to chilling injury. Further in vivo studies focusing on the immunological crosstalk between epithelial cells and gametes might explain how the immune regulators influence sperm resistance to hipothermic storage.