The -839(A/C) Polymorphism in the ECE1 Isoform b Promoter Associates With Osteoporosis and Fractures.
Karen E HansenMichael G JohnsonTonia C CarterJohn MayerNicholas S KeulerRobert Daniel BlankPublished in: Journal of the Endocrine Society (2019)
The CC genotype was associated with fewer fractures, whereas the AC genotype was associated with osteoporosis. Our small sample size and few minorities are study limitations. Findings should be tested in another cohort to confirm a link between the ECE1 -839(A/C) SNPs and osteoporosis.