Mendelian randomisation study of smoking exposure in relation to breast cancer risk.
Hanla A ParkSonja NeumeyerKyriaki MichailidouManjeet K BollaQin WangJoe G DennisThomas U AhearnIrene L AndrulisHoda Anton-CulverNatalia N AntonenkovaVolker ArndtKristan J AronsonAnnelie AugustinssonAdinda BatenLaura E Beane FreemanHeiko BecherMatthias W BeckmannSabine BehrensJavier BenitezMarina BermishevaNatalia V BogdanovaStig E BojesenHiltrud BrauchHermann BrennerSara Y BruckerBarbara BurwinkelDaniele CampaFrederico CanzianJose E CastelaoStephen J ChanockGeorgia Chenevix-TrenchChristine L Clarkenull nullDon M ConroyFergus J CouchAngela CoxSimon S CrossKamila CzeneMary B DalyPeter DevileeThilo DörkIsabel Dos-Santos-SilvaMiriam DwekDiana M EcclesA Heather EliassenChristoph EngelMikael ErikssonD Gareth EvansPeter Andreas FaschingHenrik FlygerLin FritschiMontserrat García-ClosasJosé A García-SáenzMia M GaudetGraham G GilesGord GlendonMark S GoldbergDavid E GoldgarAnna González-NeiraMervi GripPascal GuénelEric HahnenChristopher A HaimanNiclas HåkanssonPer HallUte HamannSileny HanElaine F HarknessSteven N HartWei HeBernadette Anna Maria Heemskerk-GerritsenJohn L HopperDavid J Hunternull nullnull nullAgnes JagerAnna JakubowskaEsther M JohnAudrey JungRudolf KaaksPooja Middha KapoorRenske KeemanElza KhusnutdinovaCari M KitaharaLinetta B KoppertStella KoutrosVessela N KristensenAllison W KurianJames LaceyDiether LambrechtsLoic Le MarchandWing-Yee LoJan LubińskiArto MannermaaMehdi ManoochehriSara MargolinMaria Elena MartinezDimitrios MavroudisAlfons MeindlUsha MenonRoger L MilneTaru A MuranenHeli NevanlinnaWilliam G NewmanBørge G NordestgaardKenneth OffitAndrew F OlshanHåkan OlssonTjoung-Won Park-SimonPaolo PeterlongoJulian PetoDijana Plaseska-KaranfilskaNadege PresneauPaolo RadiceGad RennertHedy S RennertAtocha RomeroEmmanouil SaloustrosElinor J SawyerMarjanka K SchmidtRita K SchmutzlerMinouk J SchoemakerLukas SchwentnerChristopher G ScottMitul ShahXiao-Ou ShuJacques SimardAnn SmeetsMelissa C SoutheyJohn J SpinelliVictoria StevensAnthony J SwerdlowRulla M TamimiWilliam J TapperJack A TaylorMary Beth TerryIan P M TomlinsonMelissa A TroesterThérèse TruongCeline M VachonElke M van VeenJoseph VijaiSophia WangCamilla WendtRobert WinqvistAlicja WolkArgyrios ZiogasAlison M DunningPaul D P PharoahDouglas F EastonWei ZhengPeter KraftJenny Chang-ClaudePublished in: British journal of cancer (2021)
Our MR study provides supportive evidence for a potential causal association with breast cancer risk for lifetime smoking exposure but not cigarettes per day among smokers.