Altered limbic functional connectivity in individuals with subjective cognitive decline: Converging and diverging findings across Chinese and German cohorts.
Xueyan JiangXiaochen HuMarcel DaamenXiaoqi WangChunqiu FanDix MeiberthAnnika SpottkeSandra RoeskeKlaus FliessbachEike Jakob SpruthSlawek AltensteinAndrea LohseNiels HansenWenzel GlanzEnise I IncesoyLaura DobischDaniel JanowitzBoris-Stephan RauchmannAlfredo RamirezIngo KilimannMatthias H J MunkXiao WangLuisa-Sophie SchneiderTatjana GabelinNina RoySteffen WolfsgruberLuca KleineidamStefan HetzerPeter DechentMichael EwersKlaus SchefflerHolger AmthauerRalph BuchertMarkus EsslerAlexander DrzezgaAxel RomingerBernd J KrauseMatthias ReimoldJosef PrillerAnja SchneiderJens WiltfangKatharina BuergerMatthias BrendelStefan TeipelChristoph LaskeOliver PetersEmrah DüzelMichael WagnerJie-Hui JiangFrank JessenHenning BoeckerYing HanPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)
Common limbic hyperconnectivity across Chinese and German subjective cognitive decline (SCD) cohorts was observed. Limbic hyperconnectivity may reflect awareness of cognition, irrespective of amyloid load. Further cross-cultural harmonization of SCD regarding Alzheimer's disease pathology is required.