AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research.

Hallvard Lauritz OlsvikTerje Johansen

Published in: PLoS biology (2023)

In this issue of PLOS Biology, Ibrahim and colleagues demonstrate how AlphaFold-multimer, an artificial intelligence-based structure prediction tool, can be used to identify sequence motifs binding to the ATG8 family of proteins central to autophagy.

Keyphrases

artificial intelligence
cell death
machine learning
endoplasmic reticulum stress
big data
deep learning
signaling pathway
oxidative stress
binding protein
protein protein
transcription factor