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TIM-3 blockade enhances IL-12-dependent antitumor immunity by promoting CD8 + T cell and XCR1 + dendritic cell spatial co-localization.

Alycia GardnerÁlvaro de Mingo PulidoKay HänggiSarah BazarganAlexis OnimusAgnieszka KasprzakJose R Conejo-GarciaKatarzyna A RejniakBrian H Ruffell
Published in: Journal for immunotherapy of cancer (2022)
T cells to cDC1-derived cytokines, with implications for the design of therapeutic strategies using antibodies against TIM-3.
Keyphrases
  • dendritic cells
  • regulatory t cells
  • cell cycle
  • immune response
  • cell proliferation