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Metabolic assessment in children with neuromuscular disorders shows risk of liver enlargement, steatosis and fibrosis.

Marie Mostue NaumeMarianne Hørby JørgensenChristina Engel Høi-HansenAlfred Peter BornJohn VissingLise BorgwardtDorte Marianne Rohde StaerkMette Cathrine Ørngreen
Published in: Acta paediatrica (Oslo, Norway : 1992) (2023)
The metabolic assessment in children with neuromuscular disorders shows an increased risk of liver enlargement, steatosis and fibrosis. Possible causes are obesity, decreased mobility, low skeletal muscle mass and for a subgroup the use of glucocorticoids. The findings suggest that monitoring liver function should be part of the nutritional assessment in patients with neuromuscular disorders.
Keyphrases
  • insulin resistance
  • skeletal muscle
  • high fat diet induced
  • high fat diet
  • type diabetes
  • clinical trial
  • body mass index
  • phase iii