Thrombocytosis and Transaminitis in Infants Born to Women With Inflammatory Bowel Disease Is Associated With Exposure to Maternal Inflammation In Utero.

Ralley E PrenticeEmma FlanaganEmily WrightWinita HardikarAlyson RossMegan BurnsLani PrideauxWilliam ConnellMiles SparrowPeter De CruzMark LustRimma GoldbergSara VogrinTessa GreeveSally Bell

Published in: Inflammatory bowel diseases (2024)

Infants born to women with IBD commonly developed thrombocytosis, elevated alkaline phosphatase, and elevated ALT. These findings were associated with exposure to maternal inflammation, elevated 6-methylmercaptopurine at delivery, and infant vaccinations and infections, and had minimal clinical consequence.

Keyphrases

birth weight
gestational age
oxidative stress
low birth weight
pregnancy outcomes
ulcerative colitis
preterm infants
body mass index