[Blockade of D1-like dopaminergic receptors suppresses Th17-cell function in multiple sclerosis].

Mikhail Melnikov Anastasia Sviridova T V Solodova A V Lopatina M V Pashenkov Alexey Boyko

Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2021)

Dopamine and blockade of D1-like dopaminergic receptors have an inhibitory effect on Th17-cell function in MS. The activation of D2-like dopaminergic receptors could mediate the inhibitory effect of dopamine on Th17-cells.

Keyphrases

multiple sclerosis
induced apoptosis
uric acid
mass spectrometry
signaling pathway
cell cycle arrest
ms ms
metabolic syndrome
cell death
cell proliferation