Impact of Metastasis Surgery and Alkylating-Agent-Based Chemotherapy on Outcomes of Metastatic Malignant Phyllodes Tumors: A Multicenter Retrospective Study.
Mathias NeronChristophe SajousSimon ThezenasSophie Piperno-NeumannFabien ReyalMarick LaéCamille ChakibaNicolas PenelThomas RyckewaertCharles HonoréFrançois BertucciAudrey MonneurSébastien SalasFlorence DuffaudEsma Saada-BouzidNicolas IsambertMehdi BrahmiIsabelle Ray-CoquardJean-Yves BlayNelly Firminnull nullPublished in: Annals of surgical oncology (2019)
The results of this study emphasize the impact of the number of metastatic sites on survival of MMPT patients and the leading role of metastasis surgery in MMPT management. If systemic therapy is used, it should include alkylating agents, which are associated with a better clinical benefit.
Keyphrases
- minimally invasive
- coronary artery bypass
- end stage renal disease
- squamous cell carcinoma
- small cell lung cancer
- ejection fraction
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- clinical trial
- metabolic syndrome
- bone marrow
- acute coronary syndrome
- atrial fibrillation
- mesenchymal stem cells
- cell therapy