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Optofluidic Particle Manipulation Platform with Nanomembrane.

Zachary J WalkerTanner N WellsEthan BellistonSage RomneySeth B WalkerMohammad Julker Neyen SampadS M SaiduzzamanRavipa LosakulHolger SchmidtAaron R Hawkins
Published in: Micromachines (2022)
We demonstrate a method for fabricating and utilizing an optofluidic particle manipulator on a silicon chip that features a 300 nm thick silicon dioxide membrane as part of a microfluidic channel. The fabrication method is based on etching silicon channels and converting the walls to silicon dioxide through thermal oxidation. Channels are encapsulated by a sacrificial polymer which fills the length of the fluid channel by way of spontaneous capillary action. The sacrificial material is then used as a mold for the formation of a nanoscale, solid-state, silicon dioxide membrane. The hollow channel is primarily used for fluid and particle transport but is capable of transmitting light over short distances and utilizes radiation pressure for particle trapping applications. The optofluidic platform features solid-core ridge waveguides which can direct light on and off of the silicon chip and intersect liquid channels. Optical loss values are characterized for liquid and solid-core structures and at interfaces. Estimates are provided for the optical power needed to trap particles of various sizes.
Keyphrases
  • high throughput
  • high resolution
  • solid state
  • ionic liquid
  • photodynamic therapy
  • high speed
  • single cell
  • nitric oxide
  • radiation therapy