Mass cytometry and transcriptomic profiling reveal body-wide pathology induced by Loxl1 deficiency.

Yu LiBingbing WuChengrui AnDeming JiangLin GongYanshan LiuYixiao LiuJun LiHongwei OuyangXiaohui Zou

Published in: Cell proliferation (2021)

This study provides an effective strategy for the screening of gene functions in multiple organs and also illustrates the important biological roles of LOXL1 in the cells of multiple organs as well as in systemic immunity.

Keyphrases

single cell
induced apoptosis
rna seq
genome wide
cell cycle arrest
dna methylation
oxidative stress
signaling pathway
replacement therapy
cell proliferation
smoking cessation