Update on Central Nervous System Effects of HIV in Adolescents and Young Adults.
Jennifer L McGuireJudith B GrinspanKelly L Jordan-SciuttoPublished in: Current HIV/AIDS reports (2023)
Adolescents and young adults account for a disproportionately high fraction of new HIV infections each year. Limited data exist regarding neurocognitive performance in this age group, but suggest impairment is at least as prevalent as in older adults, despite lower viremia, higher CD4 + T cell counts, and shorter durations of infection in adolescents/young adults. Neuroimaging and neuropathologic studies specific to this population are underway. The full impact of HIV on brain growth and development in youth with behaviorally acquired HIV has yet to be determined; it must be investigated further to develop future targeted treatment and mitigation strategies.
Keyphrases
- antiretroviral therapy
- hiv positive
- young adults
- hiv infected
- hiv testing
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- men who have sex with men
- physical activity
- south africa
- white matter
- bipolar disorder
- drug delivery
- machine learning
- electronic health record
- artificial intelligence
- cerebrospinal fluid
- high resolution
- deep learning